Diphosphonate treatment for heterotopic ossification in spinal cord injury patients.
DE Garland, B Alday, KG Venos… - … and Related Research …, 1983 - journals.lww.com
Nine patients who had spinal cord injury and were receiving diphosphonate therapy for
established neurogenic heterotopic ossification in 14 hips were followed up for an average
of 14 months. Diphosphonate therapy at a dosage of 10 mg/kg/day when prescribed an
average of 26 days after diagnosis did not prevent radiographically evident progression of
heterotopic ossification. The interval of one to 30 days between clinical diagnosis and
institution of diphosphonate treatment did not appear to affect the duration of radiographic …
established neurogenic heterotopic ossification in 14 hips were followed up for an average
of 14 months. Diphosphonate therapy at a dosage of 10 mg/kg/day when prescribed an
average of 26 days after diagnosis did not prevent radiographically evident progression of
heterotopic ossification. The interval of one to 30 days between clinical diagnosis and
institution of diphosphonate treatment did not appear to affect the duration of radiographic …
