Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice
M Kinoshita, T Uchida, A Sato, M Nakashima… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Liver Kupffer cells have been suggested to be heterogeneous
macrophage lineage cells. We explored this possibility by classifying the mouse Kupffer
cells into subpopulations and characterizing them by their phenotype and function.
METHODS: Liver mononuclear cells (MNCs) from C57BL/6 mice were isolated and their
phenotypes and functions were analyzed. The effects of clodronate liposomes and
gadolinium chloride (GdCl3) on Kupffer cells were also investigated. RESULTS …
macrophage lineage cells. We explored this possibility by classifying the mouse Kupffer
cells into subpopulations and characterizing them by their phenotype and function.
METHODS: Liver mononuclear cells (MNCs) from C57BL/6 mice were isolated and their
phenotypes and functions were analyzed. The effects of clodronate liposomes and
gadolinium chloride (GdCl3) on Kupffer cells were also investigated. RESULTS …
